Bioperfectus is your trustworthy partner encountering variation of SARS-CoV-2.

The new strain VUI 202012/01 of SARS-CoV-2 (also known as B.1.1.7 lineage) has recently caused the panic around the globe.

After a series of critical R&D analysis, we hereby officially confirm that Bioperfectus product COVID-19 Coronavirus Real Time PCR Kit and COVID-19 Coronavirus and Influenza A/B Virus Real Time PCR Kits CAN detect the new strain VUI 202012/01 of SARS-CoV-2 with reliable performance which has already been clinically proven throughout the world.

The announced mutations on the sequence of ORF1a Gene are at 3267 bp, 5388 bp, 6954 bp and 11288-11296 bps; mutations on the sequence of N Gene are at 28280 bp and 28977 bp. Targets of Bioperfectus related PCR kits are ORF1ab gene and N gene. But NONE of our detection regions are located at the announced mutations, which assures that the detection scale and performance will NOT be affected by these mutations.

Table 1 | Non-synonymous mutations and deletions inferred to occur on the branch leading to B.1.1.7 lineage

Reference: Andrew R. et al. 2020. Preliminary genomic characterisation of an emergent SARS-CoV-2 lineage in the UK defined by a novel set of spike mutations. University of Edinburgh; University of Birmingham; University of Oxford; Imperial College London; Wellcome Trust Sanger Institute; University of Cambridge; Cardiff University; MRC-University of Glasgow Centre for Virus Research. https://www.cogconsortium.uk

Introduction: Nucleotide above demonstrates the original and mutated nucleotide base of the Gene. For instance, C3267T means Cytosine (C) at 3267 bp of the gene has been mutated to Thymine (T).

If you have further questions regarding our products or would like to learn more about the variation of the virus, please feel free to contact with us at info@bioperfectus.com or visit our website www.bioperfectus.com.

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