Bioperfectus Supports Cholera Elimination


SHANGHAI, CHINA, December 5, 2022—Jiangsu Bioperfectus Technologies Co., Ltd. (hereinafter referred to as “Bioperfectus”) is pleased to launch Vibrio Cholerae Real Time PCR Kits for human diagnosis and early warning surveillance.

Cholera is an acute diarrheal infection caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae. There are many serogroups of V. cholerae, but only two – O1 and O139 – cause outbreaks. V. cholerae O1 has caused all recent outbreaks.

About 20% of those who are infected with V. cholerae develop acute watery diarrhea; approximately 20% of these individuals develop severe watery diarrhea, many also with vomiting. If these patients are not promptly and adequately treated, the loss of fluid and salts can lead to severe dehydration and death within hours. The case fatality rate in untreated cases may be 30–50%. Researchers have estimated that each year there are 1.3 to 4.0 million cases of cholera and 21 000 to 143 000 deaths worldwide due to cholera. Cholera remains a global threat to public health and an indicator of inequity and lack of social development.

Bioperfectus provides Vibrio Cholerae Real Time PCR Kits including ONE kit for human diagnosis with a CE certificate and ONE kit for environmental surveillance use to support early detection of Vibrio cholerae infection and improve early warning surveillance. Both of them are based on real-time PCR technology, for the detection of DNA from Vibrio Cholerae O1, Vibrio Cholerae O139 and Vibrio Cholerae.

V. cholerae spreads through water contaminated with feces. The aquatic environment, especially surface waters and stored drinking water, is a key component of the cholera transmission chain. To date, sampling of V. cholerae in environmental and/or sewage water has been used in different contexts applying various methods. To distinguish non-toxigenic environmental strains from toxigenic strains circulating during an outbreak, identification should include O1 serogroup determination and be completed by Polymerase Chain Reaction (PCR) identification of the cholera toxin genes.

The combination use of these two products can highly improve efficiency from prevention to early detection, to narrow the transmission scale as early as possible.

Bioperfuctus, a one-stop supplier specializing in molecular diagnostics, highly recommends the Total PCR Solution for Gastrointestinal Infectious disease, with higher throughput and higher efficiency.

Dedicated to providing laboratories with comprehensive tests of Gastrointestinal Infectious disease, Bioperfectus provides the 𝐓𝐨𝐭𝐚𝐥 𝐏𝐂𝐑 𝐒𝐨𝐥𝐮𝐭𝐢𝐨𝐧 with instruments and kits. Pioneering in molecular diagnostic, Bioperfectus are always devoted to pursuing high quality, keeps innovating, and strives to solve health problems faced by humankind for a healthier future.